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AHPA updates eight entries to the online Botanical Safety Handbook 2nd Ed. in first 2022 release

April 7, 2022

The American Herbal Products Association (AHPA) has released updates to eight botanicals via the online Botanical Safety Handbook 2nd Ed. The following entries have been updated:

  • Ocimum basilicum (basil): New studies were identified for case reports of adverse events, animal and in vitro pharmacology, acute and subchronic toxicity and cytotoxicity. The safety class for basil was changed from Class 2d to Class 1 in this revision.

  • Ocimum gratissimum (African basil): New studies were identified for human, animal, and in vitro pharmacology, acute toxicity and cytotoxicity. The safety class for African basil was changed from Class 2d to Class 1 in this revision.

  • Ocimum tenuiflorum (holy basil): A literature review identified new clinical trials, human, animal, and in vitro pharmacology studies, and new acute and subchronic toxicity studies.

  • Viburnum prunifolium (black haw): A review did not identify any new relevant safety information for black haw.

  • Viola odorata (sweet violet): A review identified additional acute toxicity studies.

  • Viola sororia (violet): A review did not identify any new relevant safety information for violet.

  • Viola tricolor (heartsease): A review did not identify any new relevant safety information for heartsease.

  • Withania somnifera (ashwagandha): New studies were identified for drug and supplement interactions, adverse events in clinical trials, case reports or adverse events, human, animal, and in vitro pharmacological data, an animal reproductive study and various toxicity studies. The safety class for ashwagandha was changed from Class 2d to Class 1 based on this review.

Get Your Copy
AHPA members can obtain a hard copy or an annual individual subscription to the online Botanical Safety Handbook for $95.00, with multi-user rates available for companies needing expanded access. Information about hard copy purchases and subscriptions can be found on the AHPA website.

Subscribers to the online Botanical Safety Handbook can review short descriptions of updated entries in the "Revisions" panel on the online version homepage when they log in. AHPA will continue to post additional updates to existing entries as well as new botanical entries. Current subscribers will be notified of these updates when they become available. The online Botanical Safety Handbook is undergoing review of existing entries and the addition of new entries to provide the latest safety information before it can be included in the next print edition of the handbook.

About AHPA's BSH
AHPA's Botanical Safety Handbook is an essential tool for anyone who manufactures, recommends, or uses herbal products. The handbook provides safety information on over 500 species of herbs, derived from data compiled from clinical trials, pharmacological and toxicological studies, medical case reports, and historical texts. All entries are reviewed by an Expert Advisory Council that includes some of the most renowned herbal and integrative medicine experts in the United States.

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